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A novel microfluidic chip for rapid screening of foodborne pathogenic bacteria

Recently, the team of Professor Lin Jianhan of the School of Information and Electrical Engineering of China Agricultural University published the latest research results in the famous journal biosensor and Bioelectronics (Biosensors and Bioelectronics) in the sensor field, entitled "A biosensor for detection of Salmonella typhimurium based on finger pressing mixing and nuclear pore membrane [...]
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How to obtain single-cell individuals by droplet microfluidic

A variety of mutated strains of COVID-19 are raging all over the world. in the face of the constantly mutating virus, scientists are still working day and night on the pathogenic mechanism of the virus, potential therapeutic targets and screening effective antibodies. Single cell study Cell research is one of the hotspots in the field [...]
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Progress in separation and analysis of tumor extracellular vesicles assisted by novel microfluidic

Recently, Sun Jiashu, a researcher at the National Nanoscience Center of the Chinese Academy of Sciences, and Zhang Shaohua, a professor at the Fifth Medical Center of the Chinese people's Liberation Army General Hospital, have developed a new microfluidic pulse filtration technology and a highly sensitive thermal swimming detection platform to achieve efficient separation and [...]
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Rapid sorting of single cell growth phenotype of microorganisms assisted by droplet microfluidic

The screening of microbial growth phenotype is a rate-limiting step in the fields of industrial breeding, enzyme directed evolution and synthetic biology. Accurate measurement of single cell growth phenotype is the key to break through the above bottlenecks. Recently, the single-cell center of Qingdao Institute of Biological Energy and process of the Chinese Academy of Sciences has [...]
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What is the speed of the micro-injection pump without continuing the pump?

As a new type of instrument with small size, simple operation and easy to use, microinjection pump (injection pump for short) has been widely used in laboratory sample injection. It can make the liquid more accurate, trace, uniform and continuous into the target instrument, and can adjust the concentration and speed of the liquid at any [...]
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Application of microfluidic chip technology in the field of biology

Microfluidic technology is regarded as one of the most capable technologies to change human beings in the 21st century, and its main application field is the biomedical field related to human fate. Application of Microfluidic Chip Technology in Gene Detection In gene detection, microfluidic chip technology is mainly used in nucleic acid amplification, separation, sequencing [...]
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Application of microfluidic technology in clinical detection

Microfluidic technology is a technology to accurately control and manipulate microscale fluid (micro-rise to skin-lift level). In the past two or three decades, thanks to the maturity of nano-manufacturing technology and the demand of biochemical technology for the manipulation of trace liquids, microfluidic technology has made rapid development. Compared with the traditional detection methods, the detection technology [...]
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Advanced techniques for gene heterogeneity research: Single-cell sequencing and on-chip gene analysis systems

Abstract Gene heterogeneity leads to the differences in cellular behaviors in a wide range, such as tumor drug-resistant mutation, epithelial-mesenchymal transition, and migration, posing significant challenges to the development of biomedicine. Traditional gene analysis methods, such as polymerase chain reaction, employ a mass of cells as the gene source, resulting in that the gene properties [...]
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Time-efficient fabrication method for 3D-printed microfluidic devices

Abstract Recent developments in 3D-printing technology have provided a time-efficient and inexpensive alternative to the fabrication of microfluidic devices. At present, 3D-printed microfluidic systems face the challenges of post-processing, non-transparency, and being time consuming, limiting their practical application. In this study, a time-efficient and inexpensive fabrication method was developed for 3D-printed microfluidic devices. The material [...]
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Functionalized Microgel Rods Interlinked into Soft Macroporous Structures for 3D Cell Culture

1 Introduction To understand interactions between living matter and artificial materials, tissue engineering research groups focus on the development of 3D scaffolds with increasingly controllable properties, reaching from biochemical interactions at molecular scale to nanoscale hydrogel networks, micrometer-scale pores, and macroscopic architectures.[1] Soft hydrogel scaffolds are conventionally formed by crosslinking a precursor solution, resulting in soft, [...]
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