In the microfluidic device, homogeneous cell-laden beads were generating by manipulating the flow rates of continuously flowing oil and cell-loaded GelMa bioink.
A microfluidic platform for highly parallel bite by bite profiling of mosquito-borne pathogen transmission
Vectorchips with integrated PDMS elastomer membranes were fabricated using a combination of laser patterning and soft lithography.
The design of the 3D BAC-eye follows the anatomical structure of an apposition compound eye (Fig. 1a). Each microlens on the BAC-eye has the same function as the corneal facet lens of a natural eye.
Cytogenetic alterations form the basis for risk stratification for multiple myeloma (MM) and guide the selection of therapy; however, current pathology assays performed on bone marrow samples can produce false-negatives due to the unpredictable distribution and rarity of MM cells. Here, we report on a microfluidic device used to facilitate CD45 depletion to enhance the detection of cytogenetic alterations in plasma cells (PCs).